Alpha DaRT is a novel radiation technology that can treat recurrent, metastatic, and locally advanced cancers. What makes this new therapy unique among radiation therapies is that, for the first time, it employs alpha particles for treatment of solid tumors. Alpha DaRT treatment consists of intratumorally-inserted radionuclides that emit alpha particles which kill tumor cells, sparing healthy cells nearby. In comparison to existing radiation therapies, it is highly effective, safe, and tolerable for patients. Alpha DaRT can potentially fill a huge unmet need for treatment of advanced cancers that are resistant or have become refractory to prior conventional therapies such as X-rays and chemotherapy, and when surgery is not an option.